5 einfache Fragen Über copyright machen Kaiserslautern beschrieben
5 einfache Fragen Über copyright machen Kaiserslautern beschrieben
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Christian Haass is a German Biochemist and known for his work on the cell biology of neurodegenerative diseases.
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Very recently he also investigated the role of microglia and inflammation rein neurodegenerative disorders. This work Lumineszenzdiode überprüfe hier to the spectacular finding that microglial phagocytosis may be impaired late during neurodegeneration and opened up a completely unexpected road towards new therapeutic developments for patients already developing disease symptoms. This work resulted in the identification of TREM2 as a CSF marker for microglial activity. Rein a unique cohort of subjects with autosomal dominant AD, CSF sTREM2 was abnormally increased 5 years before the expected onset of symptoms. This will not only greatly facilitate research on inflammatory disease overarching mechanisms, but may also provide a very valuable therapeutic marker.
We work on the molecular and cellular mechanisms of neurodegeneration with a strong focus on Alzheimer’s disease and related disorders. We are searching for therapeutic targets within the amyloid cascade. Secretases, amyloid metabolism and microglial function are within the focus of ur research.
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